Alex Karev

Hard-headed and often discourteous Resident, Alex Karev has had a series of unfortunate relationships throughout his life beginning with his mother. At an early age he had to become her defender from an abusive father and later her carer. Whilst working as a doctor he was involved with a patient, Ava, but her mental instability strained their relationship and Alex once again adopted a carer persona before Ava's admission to a psychiatric hospital. Subsequently he embarked on a relationship with Izzie Stevens and they wed, however their relationship has come under duress following Izzie's dismissal from Seattle Grace.